Article
Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections.
The Journal of infectious diseases - 1 Oct 1994
Sanders L A, van de Winkel J G, Rijkers G T, Voorhorst-Ogink M M, de Haas M, Capel P J, Zegers B J
Abstract excerpt
Fc gamma RIIa (CD32) is the sole IgG Fc receptor capable of interaction with human IgG2, the main IgG subclass of bacterial capsular polysaccharides. The two genetically determined allotypes of human Fc gamma RIIa, Fc gamma RIIa-R131 and IIa-H131 alleles, have functionally different reactivities...
Topics
- Adolescent
- Antibodies, Monoclonal
- Bacterial Infections
- Child
- Child, Preschool
- Female
- Homozygote
- Humans
- Immunoglobulin G
- Infant
- Lipopolysaccharides
- Male
- Neutrophils
- Phagocytosis
- Phenotype
- Polymorphism, Genetic
- Receptors, IgG
- Recurrence