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Article

Estimation of the size of the alloreactive NK cell repertoire: studies in individuals homozygous for the group A KIR haplotype.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2008

Fauriat Cyril, Andersson Sandra, Björklund Andreas T, Carlsten Mattias, Schaffer Marie, Björkström Niklas K, Baumann Bettina C, Michaëlsson Jakob, Ljunggren Hans-Gustaf, Malmberg Karl-Johan

Abstract excerpt

Stem cell transplantation across HLA barriers may trigger NK cell-mediated graft-vs-leukemia effects leading to improved survival for patients with hematological malignancies. However, the genetic algorithm based on killer cell Ig-like receptor (KIR) and HLA genes used to predict NK cell alloreactivity have yielded discrepant results. Accordingly, it has been difficult to define transplantation settings that...

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Identifiers

PMID: 18941190
DOI: 10.4049/jimmunol.181.9.6010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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