Article
Suppression of leu-500 mutation in topA+ Salmonella typhimurium strains. The promoter relay at work.
The Journal of biological chemistry - 6 Nov 1998
Fang M, Wu H Y
Abstract excerpt
Suppression of leu-500 mutation in Salmonella typhimurium topA- strains has been one of the most fascinating examples for the DNA supercoiling effect on transcription initiation control. Previous studies have indicated possible involvement of transcription-driven DNA supercoiling in the activation of the leu-500 promoter in topA- strains. Our recent studies have shown that ilvIH transcription activity located 1.9...
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