Article
Functional conservations of the alkaline nuclease of herpes simplex type 1 and human cytomegalovirus.
Virology - 30 Sept 1998
Gao M, Robertson B J, McCann P J, O'Boyle D R, Weller S K, Newcomb W W, Brown J C, Weinheimer S P
Abstract excerpt
The herpes simplex virus type 1 UL12 gene product, alkaline nuclease (AN), appears to be involved in viral DNA processing and capsid egress from the nucleus (Shao, L., Rapp, L. M., and Weller, S. K., Virology 196, 146-162, 1993). Although the HSV-1 AN is not absolutely essential for viral replica...
Topics
- Animals
- Chlorocebus aethiops
- Chromosome Mapping
- Cytomegalovirus
- Evolution, Molecular
- Gene Deletion
- Genes, Viral
- Genetic Complementation Test
- Herpesvirus 1, Human
- Humans
- Lac Operon
- Microscopy, Electron
- Mutation
- Ribonucleases
- Species Specificity
- Vero Cells