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Article

Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus.

Virology - 1 Sept 1993

Shao L, Rapp L M, Weller S K

Abstract excerpt

We previously described the isolation of AN-1, a null mutant of the HSV-1 alkaline nuclease gene, which is able to synthesize near wild-type levels of viral DNA and late viral proteins under nonpermissive growth conditions; these results lead us to conclude that the alkaline nuclease is not essen...

Topics

Animals
Blotting, Southern
Capsid
Cell Nucleus
DNA, Viral
Gene Amplification
Genetic Complementation Test
Hydrogen-Ion Concentration
Immunoblotting
Mutation
Restriction Mapping
Ribonucleases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Simplexvirus

Vero Cells

Source

Identifiers

PMID: 8395111
DOI: 10.1006/viro.1993.1463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8395111-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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