Article
A phosphorylation site mutant of Schizosaccharomyces pombe cdc2p fails to promote the metaphase to anaphase transition.
Molecular & general genetics : MGG - 1 Sept 1998
Gould K L, Feoktistova A, Fleig U
Abstract excerpt
The protein kinase cdc2p is a key regulator of the G1-S and G2-M cell cycle transitions in the yeast Schizosaccharomyces pombe. Activation of cdc2p is regulated by its phosphorylation state and by interaction with other proteins. We have analyzed the consequences for cell cycle progression of alt...
Topics
- Anaphase
- Apc6 Subunit, Anaphase-Promoting Complex-Cyclosome
- Base Sequence
- CDC2 Protein Kinase
- Cell Cycle
- Cell Cycle Proteins
- Cyclin B
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Suppressor
- Metaphase
- Mitosis
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Phosphorylation
- Schizosaccharomyces
- Schizosaccharomyces pombe Proteins