Mutations at sites involved in Suc1 binding inactivate Cdc2.

doi:10.1128/mcb.11.12.6177-6184.1991

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Article

Mutations at sites involved in Suc1 binding inactivate Cdc2.

Molecular and cellular biology - 1 Dec 1991

Ducommun B, Brambilla P, Draetta G

Abstract excerpt

suc1+ encodes an essential cell cycle regulator of the fission yeast Schizosaccharomyces pombe. Its product, a 13-kDa protein, interacts with the Cdc2 protein kinase. Both positive and negative effects on cell cycle progression have been attributed to Suc1. To date, the exact mechanisms and the p...

Topics

Amino Acid Sequence
Binding Sites
CDC2 Protein Kinase
Cell Cycle Proteins
Enzyme Activation
Fungal Proteins
Humans
Molecular Sequence Data
Mutation
Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Sequence Alignment

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