Article
Dopamine receptor genes and migraine with and without aura: an association study.
Headache - 1 May 2002
Shepherd A Graeme, Lea Rod A, Hutchins Colin, Jordan Kathryn L, Brimage Peter J, Griffiths Lyn R
Abstract excerpt
OBJECTIVE: To investigate the role of the dopamine receptor genes, DRD1, DRD3, and DRD5 in the pathogenesis of migraine. BACKGROUND: Migraine is a chronic debilitating disorder affecting approximately 12% of the white population. The disease shows strong familial aggregation and presumably has a genetic basis, but at present, the type and number of genes involved is unclear. The study of candidate genes can prove...
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