Article
A novel allelic variant of the human serotonin transporter gene regulatory polymorphism.
Cytogenetics and cell genetics - 1 Jan 1997
Delbrück S J, Wendel B, Grunewald I, Sander T, Morris-Rosendahl D, Crocq M A, Berrettini W H, Hoehe M R
Abstract excerpt
Allelic variation of the human serotonin transporter gene (SLC6A4) has recently been shown to modulate anxiety-related traits. A tandemly repeated sequence in close proximity to the promoter was found to be represented by a long (L) and short (S) variant, differentially modulating gene expression...
Topics
- Africa
- Alleles
- Animals
- Base Sequence
- Carrier Proteins
- Europe
- Evolution, Molecular
- Asia, Eastern
- Gene Frequency
- Gorilla gorilla
- Humans
- Membrane Glycoproteins
- Membrane Transport Proteins
- Molecular Sequence Data
- Nerve Tissue Proteins
- North America
- Polymorphism, Genetic
- Regulatory Sequences, Nucleic Acid