Article
A novel allelic variant of the human serotonin transporter gene regulatory polymorphism.
Cytogenetics and cell genetics - 1 Jan 1997
Delbrück S J, Wendel B, Grunewald I, Sander T, Morris-Rosendahl D, Crocq M A, Berrettini W H, Hoehe M R
Abstract excerpt
Allelic variation of the human serotonin transporter gene (SLC6A4) has recently been shown to modulate anxiety-related traits. A tandemly repeated sequence in close proximity to the promoter was found to be represented by a long (L) and short (S) variant, differentially modulating gene expression in vitro. Specifically, allele S, generated by a deletion of 44 bp involving repeats VI to VIII, reduced...
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