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Rho plays a key role in TGF-β1-induced proliferation and cytoskeleton rearrangement of human periodontal ligament cells.

Archives of oral biology - 1 Feb 2014

Wang Li, Wang Tingle, Song Meng, Pan Jinsong

Abstract excerpt

Human periodontal ligament cells (hPDLCs) form specialised connective tissues that influence the lifespan of the tooth. Periodontal disease is a chronic infectious disease of the periodontal supporting tissues caused by a variety of factors, particularly the loss of hPDLCs. Transforming growth factor-β1 (TGF-β1) is a multifunctional cytokine known to play an important role in periodontal disease, but little is...

Topics

Blotting, Western
Cell Proliferation
Cells, Cultured
Cytoskeleton
Humans
Periodontal Ligament
Phenotype
Signal Transduction
Transforming Growth Factor beta1
rhoA GTP-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24370186
DOI: 10.1016/j.archoralbio.2013.11.004

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