Article
Cloning and recombinant expression of mouse coagulation factor X.
Thrombosis research - 1 Oct 1998
Heidtmann H H, Kontermann R E
Abstract excerpt
Engineering of recombinant coagulation factor X variants, which can be activated by tumor-associated proteinases may lead to the development of new therapeutic molecules. However, the evaluation of such variants requires an appropriate animal model. Therefore, we isolated the complete coding sequence of mouse coagulation factor X from mouse liver cDNA by polymerase chain reaction. The deduced amino acid sequence...
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