Cloning and recombinant expression of mouse coagulation factor X.

doi:10.1016/s0049-3848(98)00110-8

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Article

Cloning and recombinant expression of mouse coagulation factor X.

Thrombosis research - 1 Oct 1998

Heidtmann H H, Kontermann R E

Abstract excerpt

Engineering of recombinant coagulation factor X variants, which can be activated by tumor-associated proteinases may lead to the development of new therapeutic molecules. However, the evaluation of such variants requires an appropriate animal model. Therefore, we isolated the complete coding sequ...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blood Coagulation
Cattle
Cell Line
Cloning, Molecular
Conserved Sequence
DNA, Complementary
Factor X
Gene Expression
Genetic Variation
Humans
In Vitro Techniques
Mice
Molecular Sequence Data
Rabbits
Recombinant Proteins

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