Article
Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient.
Journal of bacteriology - 1 Mar 1999
Abdul-Tehrani H, Hudson A J, Chang Y S, Timms A R, Hawkins C, Williams J M, Harrison P M, Guest J R, Andrews S C
Abstract excerpt
Escherichia coli contains at least two iron storage proteins, a ferritin (FtnA) and a bacterioferritin (Bfr). To investigate their specific functions, the corresponding genes (ftnA and bfr) were inactivated by replacing the chromosomal ftnA and bfr genes with disrupted derivatives containing antibiotic resistance cassettes in place of internal segments of the corresponding coding regions. Single mutants...
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