Article
Identification of a novel polymorphism in the promoter region of the tau gene highly associated to progressive supranuclear palsy in humans.
Neuroscience letters - 19 Nov 1999
Ezquerra M, Pastor P, Valldeoriola F, Molinuevo J L, Blesa R, Tolosa E, Oliva R
Abstract excerpt
An intronic polymorphism and other changes in the transcribed region of the tau gene forming a haplotype have been previously described associated to progressive supranuclear palsy (PSP). These results raised the possibility that a change at or near the tau gene could be responsible for an increased risk to develop PSP. We initiated the present work in research for potential changes in the promoter region of the...
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