Article
Significant changes in the tau A0 and A3 alleles in progressive supranuclear palsy and improved genotyping by silver detection.
Archives of neurology - 1 Aug 1998
Oliva R, Tolosa E, Ezquerra M, Molinuevo J L, Valldeoriola F, Burguera J, Calopa M, Villa M, Ballesta F
Abstract excerpt
BACKGROUND: Progressive supranuclear palsy (PSP) is characterized by intraneuronal inclusions of neurofibrillary tangles formed by aggregated tau protein. A significant association between the tau gene A0/A0 genotype and PSP recently has been reported. OBJECTIVES: To determine if a significant association between the tau gene A0/A0 genotype and PSP could be found in an independent population with a genetic...
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