Article
An extended 5'-tau susceptibility haplotype in progressive supranuclear palsy.
Neurology - 14 Nov 2000
Higgins J J, Golbe L I, De Biase A, Jankovic J, Factor S A, Adler R L
Abstract excerpt
OBJECTIVE: To confirm the association of an extended 5'-tau haplotype on chromosome 17q with the disease phenotype in clinically ascertained individuals with sporadic progressive supranuclear palsy (PSP). BACKGROUND: PSP is a neurodegenerative disease with parkinsonian signs accompanied by vertical supranuclear palsy and tau pathologic features. Previously, we documented the complete segregation of an extended...
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