Article
Reduced levels of cholesterol, phospholipids, and fatty acids in cerebrospinal fluid of Alzheimer disease patients are not related to apolipoprotein E4.
Alzheimer disease and associated disorders - 1 Sept 1998
Mulder M, Ravid R, Swaab D F, de Kloet E R, Haasdijk E D, Julk J, van der Boom J J, Havekes L M
Abstract excerpt
Apolipoprotein E4 (apoE4) has been identified as a major risk factor for Alzheimer disease (AD). Previously it has been reported that levels of apoE are reduced in cerebrospinal fluid (CSF) of AD patients. Because it is known that apoE4 affects plasma lipid metabolism, we examined whether the presence of apoE4 might correlate with an altered lipid metabolism in the CSF of control subjects and AD patients. ApoE...
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