Article
Human psoriatic skin in organ culture: comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor.
Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1998
Varani J, Kang S, Stoll S, Elder J T
Abstract excerpt
Organ cultures were established from psoriatic lesional skin of 24 different individuals and maintained for 8 days under serum-free, growth-factor-free conditions. Nonlesional skin from 14 of the same individuals and normal skin from another 12 individuals were also maintained in organ culture. A...
Topics
- Antibodies, Monoclonal
- Collagenases
- Epidermal Growth Factor
- ErbB Receptors
- Gelatinases
- Growth Substances
- Humans
- Matrix Metalloproteinase 2
- Matrix Metalloproteinase 9
- Metalloendopeptidases
- Organ Culture Techniques
- Phenotype
- Psoriasis
- Skin