Keratinocytes modulate the biosynthetic phenotype of dermal fibroblasts at a pretranslational level in a human skin equivalent.

doi:10.1007/BF00371739

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Article

Keratinocytes modulate the biosynthetic phenotype of dermal fibroblasts at a pretranslational level in a human skin equivalent.

Archives of dermatological research - 1 Jan 1995

Lacroix M, Bovy T, Nusgens B V, Lapière C M

Abstract excerpt

In this study we investigated the influence of keratinocytes on the phenotype of fibroblasts in an in vitro human skin equivalent. Keratinocytes were seeded at the surface of fibroblast-populated mechanically restrained type I collagen gels (lattices). Lattices without keratinocytes were handled...

Topics

Adult
Blotting, Northern
Cell Division
Cells, Cultured
Collagenases
Extracellular Matrix
Fibroblasts
Fibronectins
Humans
Keratinocytes
Phenotype
RNA, Messenger
Skin

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