In situ behavior of human Langerhans cells in skin organ culture.

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Article

In situ behavior of human Langerhans cells in skin organ culture.

Laboratory investigation; a journal of technical methods and pathology - 1 Oct 1995

Rambukkana A, Bos J D, Irik D, Menko W J, Kapsenberg M L, Das P K

Abstract excerpt

BACKGROUND: Epidermal Langerhans cells (ELC) play a critical role in the initiation of cutaneous immune responses. ELC are characterized by the expression of major histocompatibility complex (MHC) class II Ag and a number of adhesion/costimulatory molecules. Evidence suggests that cytokines induc...

Topics

Antigens, CD1
Culture Techniques
Cytokines
Female
Frozen Sections
Histocompatibility Antigens Class II
Humans
Immunohistochemistry
Intercellular Adhesion Molecule-1
Langerhans Cells
Male
Microscopy, Electron
Phenotype
Skin
Tumor Necrosis Factor-alpha

Source

Open in PubMed

Identifiers

PMID: 7474924

Genes

TNF
HECA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7474924-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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