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Article

In situ behavior of human Langerhans cells in skin organ culture.

Laboratory investigation; a journal of technical methods and pathology - 1 Oct 1995

Rambukkana A, Bos J D, Irik D, Menko W J, Kapsenberg M L, Das P K

Abstract excerpt

BACKGROUND: Epidermal Langerhans cells (ELC) play a critical role in the initiation of cutaneous immune responses. ELC are characterized by the expression of major histocompatibility complex (MHC) class II Ag and a number of adhesion/costimulatory molecules. Evidence suggests that cytokines induced within the epidermis regulate the functions of ELC, including their phenotypic expression. In the human system, no...

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Source

Identifiers

PMID: 7474924

Genes

TNF
HECA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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