Article
Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin.
The Journal of investigative dermatology - 1 Apr 2000
Ting K M, Rothaupt D, McCormick T S, Hammerberg C, Chen G, Gilliam A C, Stevens S, Culp L, Cooper K D
Abstract excerpt
The extracellular matrix protein, Fn, has critical functions in cell attachment, migration, differentiation, and proliferation. We have previously shown that fibronectin (Fn) is abnormally expressed and potentiates entry into the cell cycle of basal keratinocytes in uninvolved psoriatic skin, in combination with T cell lymphokines. It is not known what type of Fn is present in psoriatic skin, however, and how...
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