Epithelial cell invasion of the stroma in human skin organ culture.

doi:10.2741/1453

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Article

Epithelial cell invasion of the stroma in human skin organ culture.

Frontiers in bioscience : a journal and virtual library - 1 Sept 2004

Varani James

Abstract excerpt

Invasion of the surrounding tissue by malignant epithelial cells is a complex process. It involves degradation of basement membrane and stromal connective tissue elements and movement of tumor cells into and through the partially-degraded matrix. While the process of tumor cell invasion has been extensively studied in simple two-dimensional or three-dimensional assay systems, it is difficult to know how the...

Topics

Animals
Cell Adhesion
Cell Line, Tumor
Cell Movement
Culture Media
Culture Media, Serum-Free
Dermis
Epithelial Cells
Fibronectins
Growth Substances
Humans
Matrix Metalloproteinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Organ Culture Techniques

Phenotype

Signal Transduction

Skin

Skin Neoplasms

Stromal Cells

Source

Open in PubMed

Identifiers

PMID: 15353331
DOI: 10.2741/1453

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