Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration and significance of heparin-binding epidermal-growth-factor-like growth factor in psoriatic epidermis.

Dermatology (Basel, Switzerland) - 1 Jan 2003

Zheng Yan, Peng Zhenhui, Wang Yili, Tan Shengshun, Xi Yanping, Wang Guorong

Abstract excerpt

BACKGROUND: Heparin-binding epidermal-growth-factor-like growth factor (HB-EGF) has proved to be a mitogen of keratinocytes, which may be involved in the pathogenesis of inflammatory diseases, but its mechanism in psoriasis remains unknown. OBJECTIVE: To investigate the alteration of HB-EGF in the epidermis of active psoriasis vulgaris. METHODS: The expression of HB-EGF in normal skin tissues, uninvolved tissues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biopsy, Needle
Share to Epidermal Growth Factor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Heparin-binding EGF-like Growth Factor

Share to In Situ Hybridization

Share to Intercellular Signaling Peptides and Proteins

Share to Psoriasis

Share to Reference Values

Share to Severity of Illness Index

Source

Identifiers

PMID: 12835543
DOI: 10.1159/000070936

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration and significance of heparin-binding epidermal-growth-factor-like growth factor in psoriatic epidermis.PMID 12835543Read ↗

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a mediator of multiple physiological and pathological pathways.Semantic proximity Read ↗

Notch Signaling May Be Involved in the Abnormal Differentiation of Epidermal Keratinocytes in PsoriasisSemantic proximity Read ↗

Gene expression profile of dermal mesenchymal stem cells from patients with psoriasisSemantic proximity Read ↗

Human EGF receptor (HER) family and heregulin members are differentially expressed in epidermal keratinocytes and modulate differentiation.Semantic proximity Read ↗

Human psoriatic skin in organ culture: comparison with normal skin exposed to exogenous growth factors and effects of an antibody to the EGF receptor.Semantic proximity Read ↗

Basic Fibroblast Growth Factor Influences Epidermal Homeostasis of Living Skin Equivalents through Affecting Fibroblast Phenotypes and Functions.Semantic proximity Read ↗

Heparanase is preferentially expressed in human psoriatic lesions and induces development of psoriasiform skin inflammation in mice.Semantic proximity Read ↗

Skin-derived antileukoproteinase (SKALP) and epidermal fatty acid-binding protein (E-FABP): two novel markers of the psoriatic phenotype that respond differentially to topical steroid.Semantic proximity Read ↗

The Roles of Growth Factors in Keratinocyte MigrationSemantic proximity Read ↗

Fibroblast growth factor-binding protein facilitates the growth and migration of skin-derived precursors.Semantic proximity Read ↗

Abnormal dermal microvascular endothelial cells in psoriatic excessive angiogenesis.Semantic proximity Read ↗

Quantitative determination of EGF-R during epidermal wound healing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.