Article
Cytotoxic T lymphocyte mediated recognition of human pancreatic cancer cells.
International journal of cancer - 1 May 2002
Peiper Matthias, Sato Takeo, Streichert Thomas, Eisenberger Claus Ferdinand, Knoefel Wolfram Trudo, Izbicki Jakob Robert
Abstract excerpt
T lymphocytes play an important role in tumor rejection and their response to human malignant melanoma has been well documented. In contrast, the existence of cytotoxic T lymphocytes (CTL) to pancreatic cancer remains unclear. Tumor-associated lymphocytes (TAL) and peripheral blood monocytes (PBMC) were isolated from pancreatic cancer patients. Tumor-specific CTL were generated from TAL and PBMC using solid-phase...
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