Article
Role of sonic hedgehog in branchiomotor neuron induction in zebrafish.
Mechanisms of development - 1 Aug 1998
Chandrasekhar A, Warren J T, Takahashi K, Schauerte H E, van Eeden F J, Haffter P, Kuwada J Y
Abstract excerpt
The role of zebrafish hedgehog genes in branchiomotor neuron development was analyzed by examining mutations that affect the expression of the hedgehog genes and by overexpressing these genes in embryos. In cyclops mutants, reduction in sonic hedgehog (shh) expression, and elimination of tiggy-wi...
Topics
- Animals
- Branchial Region
- Cell Nucleus
- Embryo, Nonmammalian
- Embryonic Induction
- Gene Expression Regulation, Developmental
- Hedgehog Proteins
- Intracellular Signaling Peptides and Proteins
- Motor Neurons
- Mutation
- Nervous System
- Neurons
- Proteins
- Rhombencephalon
- Spinal Cord
- Trans-Activators
- Transforming Growth Factor beta
- Zebrafish