Article
Gli2 mediation of hedgehog signals in slow muscle induction in zebrafish.
Differentiation; research in biological diversity - 1 Mar 2001
Du S J, Dienhart M
Abstract excerpt
Zebrafish skeletal muscles are composed of two major types of muscle fibers, broadly classified as fast or slow fibers. Recent studies have demonstrated that members of the Hedgehog (Hh) family induce the formation of slow muscle fibers. Hedgehog signals are secreted proteins that function through the transcription factor Glis. We report here the characterization of a zebrafish Gli2 expression in slow and fast...
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