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Article

Hedgehog signaling is required for primary motoneuron induction in zebrafish.

Development (Cambridge, England) - 1 Sept 2001

Lewis K E, Eisen J S

Abstract excerpt

Sonic hedgehog (Shh) is crucial for motoneuron development in chick and mouse. However, zebrafish embryos homozygous for a deletion of the shh locus have normal numbers of motoneurons, raising the possibility that zebrafish motoneurons may be specified differently. Unlike other vertebrates, zebrafish express three hh genes in the embryonic midline: shh, echidna hedgehog (ehh) and tiggywinkle hedgehog (twhh)....

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Identifiers

PMID: 11566854
DOI: 10.1242/dev.128.18.3485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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