Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium.

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Article

Polymorphic expression of the UDP-glucuronosyltransferase UGT1A gene locus in human gastric epithelium.

Molecular pharmacology - 1 Oct 1998

Strassburg C P, Nguyen N, Manns M P, Tukey R H

Abstract excerpt

The human UDP-glucuronosyltransferase (UGT) 1A (UGT1A) locus is regulated in a tissue specific fashion in liver and extrahepatic tissues. Three extrahepatic UGT1A proteins, UGT1A7, UGT1A8, and UGT1A10, have been discovered and are believed to contribute to the diversity of extrahepatic glucuronid...

Topics

Adenocarcinoma
Adult
Aged
Epithelium
Exons
Female
Gene Expression Regulation, Enzymologic
Gene Expression Regulation, Neoplastic
Genetic Variation
Glucuronosyltransferase
Humans
Male
Middle Aged
Polymorphism, Genetic
Protein Isoforms
RNA, Messenger
RNA, Neoplasm
Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 9765507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9765507-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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