Article
Adenovirus endocytosis requires actin cytoskeleton reorganization mediated by Rho family GTPases.
Journal of virology - 1 Nov 1998
Li E, Stupack D, Bokoch G M, Nemerow G R
Abstract excerpt
Adenovirus (Ad) endocytosis via alphav integrins requires activation of the lipid kinase phosphatidylinositol-3-OH kinase (PI3K). Previous studies have linked PI3K activity to both the Ras and Rho signaling cascades, each of which has the capacity to alter the host cell actin cytoskeleton. Ad int...
Topics
- Actins
- Adenovirus Infections, Human
- Adenoviruses, Human
- Androstadienes
- Biopolymers
- Cell Cycle Proteins
- Cell Line
- Cytoskeleton
- Endocytosis
- Enzyme Activation
- Enzyme Inhibitors
- GTP Phosphohydrolases
- GTP-Binding Proteins
- GTPase-Activating Proteins
- Humans
- Membrane Proteins
- Mutation
- Phosphatidylinositol 3-Kinases