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Article

Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA.

Molecular and cellular biology - 1 Oct 2003

Moreau Violaine, Tatin Florence, Varon Christine, Génot Elisabeth

Abstract excerpt

Members of the Rho GTPase family play a central role in the orchestration of cytoskeletal rearrangements, which are of prime importance in endothelial cell physiology. To explore their role in this specialized cell type, we used the bacterial toxin cytotoxic necrotizing factor 1 (CNF1) as a Rho GTPase activator. Punctate filamentous actin structures appeared along the ventral plasma membrane of endothelial cells...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12972601
DOI: 10.1128/MCB.23.19.6809-6822.2003
PMCID: PMC193918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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