Article
HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy.
AIDS (London, England) - 10 Sept 1998
Craig C, Race E, Sheldon J, Whittaker L, Gilbert S, Moffatt A, Rose J, Dissanayeke S, Chirn G W, Duncan I B, Cammack N
Abstract excerpt
OBJECTIVE: To examine the relationship between HIV protease genotype and altered protease inhibitor sensitivity of isolates from patients after therapy with saquinavir (SQV) in its hard gelatin formulation. DESIGN: Forty-one post-therapy isolates and corresponding baseline samples were obtained from 37 patients in four different clinical trials after therapy with SQV for 16-147 weeks. Post-therapy isolates were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.