Article
HIV protease genotype and viral sensitivity to HIV protease inhibitors following saquinavir therapy.
AIDS (London, England) - 10 Sept 1998
Craig C, Race E, Sheldon J, Whittaker L, Gilbert S, Moffatt A, Rose J, Dissanayeke S, Chirn G W, Duncan I B, Cammack N
Abstract excerpt
OBJECTIVE: To examine the relationship between HIV protease genotype and altered protease inhibitor sensitivity of isolates from patients after therapy with saquinavir (SQV) in its hard gelatin formulation. DESIGN: Forty-one post-therapy isolates and corresponding baseline samples were obtained f...
Topics
- Amino Acid Substitution
- Carbamates
- Clinical Trials as Topic
- DNA, Viral
- Databases, Factual
- Furans
- Genetic Linkage
- Genotype
- HIV Infections
- HIV Protease
- HIV Protease Inhibitors
- Humans
- Indinavir
- Methionine
- Nelfinavir
- Phenotype
- Polymerase Chain Reaction
- Ritonavir