Article
Analysis of genotypic and phenotypic clinical cut-off levels for ritonavir-boosted saquinavir.
HIV medicine - 1 Mar 2006
Hill A, Walmsley S, Clotet B, Molto J
Abstract excerpt
There is a need for new, clinically relevant interpretation algorithms for genotypic and phenotypic resistance for ritonavir-boosted saquinavir (SQV/r) at the current approved dosage [1000/100 mg twice a day (bid)]. Clinical cut-off levels, which correlate baseline measures of resistance with HIV RNA responses in large cohorts or clinical trials, are the ideal reference for developing such algorithms. Cut-off...
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