Article
Dietary salt excess unmasks blunted aldosterone suppression and sodium retention in the stroke-prone phenotype of the spontaneously hypertensive rat.
Journal of hypertension - 1 Aug 1993
Volpe M, Rubattu S, Ganten D, Enea I, Russo R, Lembo G, Mirante A, Condorelli G, Trimarco B
Abstract excerpt
OBJECTIVE: The mechanisms underlying the accelerating effect of high salt intake on the development of vascular injury in the stroke-prone phenotype of spontaneously hypertensive rats (SHRSP) are still not clear. The aim of the present study was to determine whether young SHRSP can excrete a dietary excess of sodium and to characterize the associated hormonal responses. METHODS: Sodium balance and hormonal...
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