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Article

C4d DNA sequences of two infrequent human allotypes (C4A13 and C4B12) and the presence of signal sequences enhancing recombination.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1998

Martínez-Quiles N, Paz-Artal E, Moreno-Pelayo M A, Longás J, Ferre-López S, Rosal M, Arnaiz-Villena A

Abstract excerpt

The DNA sequences of the polymorphic region (C4d) that belong to the infrequent complement C4 allotypes C4A13 and C4B12 have been obtained. In addition, C4A4 and C4B2 C4d sequences have been completed. C4A13 shows a new combination of amino acids at the following polymorphic positions: Asp1054, Pro1101 Cys1102, Leu1105, Asp1106, Asn1157, Ala1188, and Arg1191. These amino acids conform to the antigenic...

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PMID: 9759862

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