Article
An investigation of the C4 gene arrangement in ethnic Chinese (Taiwanese).
International journal of immunogenetics - 1 Aug 2008
Tseng Yung-Te, Lee Hsien-Hsiung, Lee Yann-Jinn
Abstract excerpt
C4 complement components are encoded by two genes, C4A and C4B , located on chromosome 6p21.3 of the major histocompatibility complex class III region. The isotypic residues at position 1101-1106 of the C4A gene contain the Pro-Cys-Pro-Val-Leu-Asp sequence which has a higher affinity for binding amino group-containing antigens, while C4B contains the Leu-Ser-Pro-Val-Ileu-His sequence which has a higher affinity...
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