Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allelic affinities between the F13A common gene products inferred by the analysis of an (AAAG)n STR polymorphism within the 5' untranslated region.

Human heredity - 1 Jan 2000

Prata M J, Miranda C, Rocha J, Amorim A

Abstract excerpt

Factor XIII a subunit (F13A) is the last enzyme in the blood coagulation cascade. It is characterized by extensive genetic polymorphism defined by 4 common alleles, F13A*1A, 1B, 2A and 2B and a few rare variants, some responsible for severe coagulation deficiencies. In order to infer the evolutionary affinities between the common F13A alleles we have applied PCR techniques to study, in a Northern Portuguese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5' Untranslated Regions
Share to Alleles
Share to Factor XIII

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Models, Genetic

Share to Polymorphism, Genetic

Share to Tandem Repeat Sequences

Source

Identifiers

PMID: 10686499
DOI: 10.1159/000022913

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allelic affinities between the F13A common gene products inferred by the analysis of an (AAAG)n STR polymorphism within the 5' untranslated region.PMID 10686499Read ↗

Molecular basis for subtypic differences of the "a" subunit of coagulation factor XIII with description of the genesis of the subtypes.Semantic proximity Read ↗

Mutations affecting disulphide bonds contribute to a fairly common prevalence of F13B gene defects: results of a genetic study in 14 families with factor XIII B deficiency.Semantic proximity Read ↗

Formal and population genetics of F13A and FUCA1 polymorphisms in northern Portugal.Semantic proximity Read ↗

High incidence of FXI deficiency in a Spanish town caused by 11 different mutations and the first duplication of F11: Results from the Yecla study.Semantic proximity Read ↗

Activity and levels of factor XIII in a Venezuelan admixed population: association with rs5985 (Val35Leu) and STR F13A01 polymorphisms.Semantic proximity Read ↗

Distribution of F13A phenotypes in Spain: a particularly high frequency of the F13A*2 allele.Semantic proximity Read ↗

Age and Origin of the Founder Antithrombin Budapest 3 (p.Leu131Phe) Mutation; Its High Prevalence in the Roma Population and Its Association With Cardiovascular DiseasesSemantic proximity Read ↗

Gene-centric approach identifies new and known loci for FVIII activity and VWF antigen levels in European Americans and African Americans.Semantic proximity Read ↗

Inherited bleeding disorders: results from the Italian Regional Haemophilia Centre of Pescara.Semantic proximity Read ↗

Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians.Semantic proximity Read ↗

VWA STR genotyping: further inconsistencies between Perkin-Elmer and Promega kits.Semantic proximity Read ↗

Reliable genotyping of the coagulation Factor XIII-A Leu34 variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.