Article
Identification of two new C4 alleles by DNA sequencing and evidence for a historical recombination of serologically defined C4A and C4B alleles.
Tissue antigens - 1 Mar 2004
Hui J, Oka A, Tomizawa M, Tay G K, Kulski J K, Penhale W J, Iaschi S P A, Makino S, Tamiya G, Inoko H
Abstract excerpt
Nucleotide polymorphisms of the C4 genes were investigated by direct sequencing of seven different homozygous typing cells from the 10IHW panels. Two novel sequences were identified within the C4d region of the C4 genes. Our sequencing analyses extend previous findings suggesting that a recombination hot spot is likely to have occurred between codon positions 1157 and 1186 within the C4d region. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
