Article
Improved method for the allelic definition of C4A and C4B polymorphism (HLA class III).
BioTechniques - 1 May 2001
Zorzetto M, Campo I, Cortelazzo A G, Panelli S, Cuccia M
Abstract excerpt
The polymorphism of the fourth component of human serum complement (C4) is well established at the proteinic level; at the DNA level in the analysis of C4A and C4B gene polymorphism, the PCR technique is not widely and routinely used because it is time consuming and still presents reproducibility problems. This is a serious problem because only PCR genotyping allows the establishment of Rodgers-Chido reverse...
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