Article
Function of steroidogenic factor 1 (SF1) ligand-binding domain in gene activation and interaction with AP1.
Biochemical and biophysical research communications - 18 Sept 1998
Li L A, Lala D, Chung B C
Abstract excerpt
The nuclear receptor SF1 is an essential mediator in ventromedial hypothalamus-pituitary-gonadal development. As with other nuclear receptors, SF1 possesses a DNA-binding domain composed of two zinc fingers and a ligand-binding domain containing a ligand-dependent activation sequence termed AF2....
Topics
- Animals
- Binding Sites
- Cell Line
- DNA-Binding Proteins
- Fushi Tarazu Transcription Factors
- Gonads
- Homeodomain Proteins
- Humans
- Hypothalamus
- Mice
- Mutation
- Peroxidases
- Peroxiredoxins
- Pituitary Gland
- Receptors, Cytoplasmic and Nuclear
- Steroidogenic Factor 1
- Thyroid Hormones
- Transcription Factors