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Article

Blastic mantle cell lymphoma associated with Burkitt‐type translocation and hypodiploidy

1 Oct 2001

Abstract excerpt

Two elderly men with stage IV mantle cell lymphoma (MCL) rapidly developed a leukaemic phase with unusually high blast counts that proved fatal. One lymph node biopsy showed diffuse MCL, the other blastic morphology. In addition to t(11;14), there were t(8;14) and t(1;19) in case 1 and dup(8)(q24q13) in case 2. Fluorescence in situ hybridization revealed genomic fusion of IgH/MYC genes in case 1 and an extra copy...

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Identifiers

PMID: 11722412
DOI: 10.1046/j.1365-2141.2001.03056.x

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