Article
Sequence analysis proves clonal identity in five patients with typical and blastoid mantle cell lymphoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2007
Yin C Cameron, Medeiros L Jeffrey, Cromwell Candy C, Mehta Ashwini P, Lin Pei, Luthra Rajyalakshmi, Abruzzo Lynne V
Abstract excerpt
Mantle cell lymphoma (MCL) is typically composed of small irregular lymphoid cells. Blastoid variants, composed of lymphoblast-like (classic type) or large (pleomorphic type) cells, arise de novo or in patients with typical MCL. Although it has been assumed that blastoid variant represents histologic transformation of typical MCL, the clonal relationship between the two tumors has rarely been assessed at the...
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