Article
Identification and characterization of a novel member of the fibroblast growth factor family.
The European journal of neuroscience - 1 May 1998
Greene J M, Li Y L, Yourey P A, Gruber J, Carter K C, Shell B K, Dillon P A, Florence C, Duan D R, Blunt A, Ornitz D M, Ruben S M, Alderson R F
Abstract excerpt
A new member of the fibroblast growth factor (FGF) family, FGF-13, has been molecularly cloned as a result of high throughput sequencing of a human ovarian cancer cell library. The open reading frame of the novel human gene (1419 bp) encodes for a protein of 216 a.a. with a molecular weight of 22 kDa. The FGF-13 sequence contains an amino-terminal hydrophobic region of 23 a.a. characteristic of a signal secretion...
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