Article
Sequence diversity of SIV(Mne) Nef in vivo and in vitro.
Journal of medical primatology - 1 Jan 2000
Heidecker G, Muñoz H, Lloyd P A, Hodge D R, Pei G K, Rick S W, Brehm K, Ruscetti F W, Kuller L, Polacino P, Hu S L, Morton W R, Benveniste R E
Abstract excerpt
We have compared nef gene sequences isolated by PCR from peripheral blood lymphocyte DNA of macaques which had been inoculated with either biologically or molecularly cloned SIV(Mne). Two samples from each animal obtained either early after infection (week 2-8) or after significant CD4+ depletion...
Topics
- Amino Acid Sequence
- Animals
- Cells, Cultured
- DNA Primers
- Gene Products, nef
- Genes, nef
- Genetic Variation
- Lymphocytes
- Macaca nemestrina
- Models, Molecular
- Molecular Sequence Data
- Polymerase Chain Reaction
- Protein Conformation
- Sequence Alignment
- Simian Acquired Immunodeficiency Syndrome