Article
Macaques infected with cloned simian immunodeficiency virus show recurring nef gene alterations.
Virology - 30 Sept 1998
Heidecker G, Muñoz H, Lloyd P, Hodge D, Ruscetti F W, Morton W R, Hu S, Benveniste R E
Abstract excerpt
We compared nef gene sequences isolated by polymerase chain reaction from peripheral blood lymphocyte DNA of macaques that had been inoculated with either biologically (E11S) or molecularly (clone 8) cloned SIV/Mne. Two samples from each animal obtained either early (weeks 2-8) or late (weeks 21-...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Gene Products, nef
- Genes, nef
- Macaca fascicularis
- Macaca nemestrina
- Molecular Sequence Data
- Mutation
- Open Reading Frames
- Proviruses
- Restriction Mapping
- Sequence Homology, Amino Acid
- Simian Acquired Immunodeficiency Syndrome
- Simian Immunodeficiency Virus
- Virus Replication