Article
Genetic and molecular analysis of DNA43 and DNA52: two new cell-cycle genes in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Apr 1992
Solomon N A, Wright M B, Chang S, Buckley A M, Dumas L B, Gaber R F
Abstract excerpt
Two Saccharomyces cerevisiae genes previously unknown to be required for DNA synthesis have been identified by screening a collection of temperature-sensitive mutants. The effects of mutations in DNA43 and DNA52 on the rate of S phase DNA synthesis were detected by monitoring DNA synthesis in synchronous populations that were obtained by isopycnic density centrifugation. dna43-1 and dna52-1 cells undergo...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle Proteins
- Cell Nucleus
- Chromosomal Proteins, Non-Histone
- Chromosome Mapping
- Chromosomes, Fungal
- Cloning, Molecular
- DNA Mutational Analysis
- DNA, Fungal
