Article
Modulation of cytokeratin subtype, EGF receptor, and androgen receptor expression during progression of prostate cancer.
Human pathology - 1 Sept 1998
Gil-Diez de Medina S, Salomon L, Colombel M, Abbou C C, Bellot J, Thiery J P, Radvanyi F, Van der Kwast T H, Chopin D K
Abstract excerpt
After initial regression in response to androgen deprivation, most prostate cancers develop resistance to endocrine therapy. Identification of cellular and molecular changes occurring during endocrine therapy-induced regression and subsequent hormone insensitivity may point to mechanisms underlying the transition to hormone-independent prostate cancer. A series of untreated (n = 24), regressed (n = 15), and...
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