Article
Molecular mechanisms in hormone-resistant prostate cancer.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 1 Jan 2000
Roznovanu Silvia Lăcrămioara, Amălinci Cornelia, Rădulescu Doiniţa
Abstract excerpt
Prostate cancer is the most common malignancy in males. Despite the efforts for an early diagnosis, approximately one third of the cases are diagnosed in advanced clinical stages. Prostatic cancer, as the function of normal prostate is dependent upon androgens. So, androgenic deprivation represents an effective treatment especially in advanced cases. Although, the majority of patients will initially respond to...
Topics
- Androgens
- Epidermal Growth Factor
- Fibroblast Growth Factor 2
- Genes, bcl-2
- Genes, p53
- Genomic Instability
- Growth Substances
- Humans
- Male
- Mutation
- Neoplasms, Hormone-Dependent