Article
Multivariate analysis of laminar patterns of neurodegeneration in posterior cingulate cortex in Alzheimer's disease.
Experimental neurology - 1 Sept 1998
Vogt B A, Vogt L J, Vrana K E, Gioia L, Meadows R S, Challa V R, Hof P R, Van Hoesen G W
Abstract excerpt
Posterior cingulate cortex is the site of earliest reductions in glucose metabolism and qualitatively different laminar patterns of neurodegeneration in Alzheimer's disease (AD). This study used multivariate analyses of area 23 in 72 cases of definite AD to assess relationships between laminar patterns of neurodegeneration, neurofibrillary tangle (NFT) and senile plaque (SP) densities, age of disease onset and...
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