Article
Villous B cells of the small intestine are specialized for invariant NK T cell dependence.
Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2008
Velázquez Peter, Wei Bo, McPherson Michael, Mendoza Lesley Marie A, Nguyen Sandra L, Turovskaya Olga, Kronenberg Mitchell, Huang Tiffany T, Schrage Matthew, Lobato Lynn N, Fujiwara Daisuke, Brewer Sarah, Arditi Moshe, Cheng Genhong, Sartor R Balfour, Newberry Rodney D, Braun Jonathan
Abstract excerpt
B cells are important in mucosal microbial homeostasis through their well-known role in secretory IgA production and their emerging role in mucosal immunoregulation. Several specialized intraintestinal B cell compartments have been characterized, but the nature of conventional B cells in the lamina propria is poorly understood. In this study, we identify a B cell population predominantly composed of surface...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.