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Article

Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 1998

Schunkert H, Hense H W, Döring A, Riegger G A, Siffert W

Abstract excerpt

Gi proteins mediate the intracellular effects of many vasoactive and proliferative stimuli. Recently such signaling was found to be enhanced in cultured cells of some hypertensive subjects. A polymorphism at position 825 (C-->T) of the G protein beta3 subunit gene (GNB3) was strictly related to this phenotype. The aim of the present investigation was to test the association between this polymorphism and blood...

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Source

Identifiers

PMID: 9740618
DOI: 10.1161/01.hyp.32.3.510

Genes

GNB3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels.PMID 9740618Read ↗

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G protein beta3 subunit gene 825T allele is associated with increased left ventricular mass in young subjects with mild hypertension.Semantic proximity Read ↗

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