Article
Differential chemical probing of a group II self-splicing intron identifies bases involved in tertiary interactions and supports an alternative secondary structure model of domain V.
RNA (New York, N.Y.) - 1 Sept 1998
Costa M, Christian E L, Michel F
Abstract excerpt
Dimethyl sulfate modification was used to probe for tertiary structural elements in the group II intron PI.LSU/2 from the mitochondrial pre-ribosomal RNA of the brown alga Pylaiella littoralis. Modification of the lariat form of the intron under conditions that allow both native folding and conformational homogeneity is found to be generally consistent with secondary and tertiary structural features identified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.